Search results for "Reproductive Health"

showing 10 items of 58 documents

Maternal Inheritance of a Recessive RBP4 Defect in Canine Congenital Eye Disease

2018

SUMMARY Maternally skewed transmission of traits has been associated with genomic imprinting and oocyte-derived mRNA. We report canine congenital eye malformations, caused by an amino acid deletion (K12del) near the N terminus of retinol-binding protein (RBP4). The disease is only expressed when both dam and offspring are deletion homozygotes. RBP carries vitamin A (retinol) from hepatic stores to peripheral tissues, including the placenta and developing eye, where it is required to synthesize retinoic acid. Gestational vitamin A deficiency is a known risk factor for ocular birth defects. The K12del mutation disrupts RBP folding in vivo, decreasing its secretion from hepatocytes to serum. T…

0301 basic medicineMaleNon-Mendelian inheritanceProtein Foldingcongenital eye defectEye Diseasesgenetic structuresNATIVE DISULFIDE BONDSMedical PhysiologyRetinoic acidReproductive health and childbirth413 Veterinary scienceMicrophthalmiavitamin Achemistry.chemical_compoundPlasmaA-vitamiini2.1 Biological and endogenous factorsMicrophthalmosPrealbuminCRYSTAL-STRUCTUREAetiologyBase Pairinglcsh:QH301-705.5Sequence DeletionPediatricwhole genome sequencingVITAMIN-A-DEFICIENCYANOPHTHALMIAPenetrancePedigreemedicine.anatomical_structurePhenotypeFemalemedicine.medical_specialtyGenotypeENDOPLASMIC-RETICULUMGenes RecessiveMETABOLISMBiologyGeneral Biochemistry Genetics and Molecular BiologyArticle03 medical and health sciencesDogscanine geneticsInternal medicinePlacentaRETINOL-BINDING-PROTEINGeneticsmedicineAnimalsHumansRecessiveMALFORMATIONSBIOCHEMICAL BASISAmino Acid SequenceAlleleEye Disease and Disorders of VisionNutritiongenome-wide association study030102 biochemistry & molecular biologywestern blottingMUTATIONSta1184RBP4maternal inheritancemedicine.diseaseRetinol-Binding ProteinsRetinol binding proteinnuclear magnetic resonance030104 developmental biologyEndocrinologychemistryGeneslcsh:Biology (General)microphthalmiaGenetic LociHela Cells1182 Biochemistry cell and molecular biologyCongenital Structural Anomalies3111 BiomedicineBiochemistry and Cell BiologyDigestive DiseasesGenomic imprintingRetinol-Binding Proteins PlasmaHeLa Cells
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Global, regional, and national levels of maternal mortality, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

2016

BACKGROUND: In transitioning from the Millennium Development Goal to the Sustainable Development Goal era, it is imperative to comprehensively assess progress toward reducing maternal mortality to identify areas of success, remaining challenges, and frame policy discussions. We aimed to quantify maternal mortality throughout the world by underlying cause and age from 1990 to 2015.METHODS: We estimated maternal mortality at the global, regional, and national levels from 1990 to 2015 for ages 10-54 years by systematically compiling and processing all available data sources from 186 of 195 countries and territories, 11 of which were analysed at the subnational level. We quantified eight underl…

0301 basic medicinePediatricsNutrition and DiseaseMILLENNIUM DEVELOPMENT GOALSSUSTAINABLE DEVELOPMENT GOALSANTENATAL CAREGlobal Health0302 clinical medicineVoeding en Ziekte11. SustainabilityGlobal healthHQHealthcare FinancingEMERGENCY OBSTETRIC CARE030212 general & internal medicineCooperative Behavior10. No inequalityReproductive healthMedicine(all)education.field_of_study030219 obstetrics & reproductive medicineMedicine (all)1. No povertyObstetrics and GynecologyPublic Health Global Health Social Medicine and EpidemiologyPrenatal CareGeneral Medicine11 Medical And Health SciencesLOW-RESOURCE SETTINGS3142 Public health care science environmental and occupational healthFamily Planning Service3. Good healthGBD 2015 Maternal Mortality CollaboratorsGovernment ProgramsMaternal MortalityReproductive HealthFamily Planning ServicesMaternal deathHEALTHLife Sciences & BiomedicineHumanCOUNTRIESmedicine.medical_specialtyPopulation610Prenatal careArticle03 medical and health sciencesMedicine General & InternalSDG 3 - Good Health and Well-beingCASH TRANSFER PROGRAMEnvironmental healthGeneral & Internal Medicineparasitic diseasesmedicineLife ScienceQUALITYHumansGlobal Burden of Disease StudyeducationVLAGScience & TechnologyMedical Assistancebusiness.industryKlinisk medicinParturitionObstetric transitionmedicine.diseaseQPInfant mortalityFolkhälsovetenskap global hälsa socialmedicin och epidemiologiStandardized mortality ratio030104 developmental biologyRISK-FACTORSRGClinical MedicinebusinessRA
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Infecciones de transmisión sexual en población joven ¿qué mantiene su exposición al riesgo?

2019

Las infecciones de transmisión sexual, suponen uno de los riesgos más prevalentes entre lapoblación joven. En España, su incidencia se ha incrementado en los últimos años, siendo uno los países más afectados de Europa. Si bien se han llevado a cabo distintos esfuerzos preventivos para revertir la situación, no han mostrado la eficacia esperada. Por eso, resulta necesario profundizar en el análisis de aquellos factores que podrían mantener las conductas de riesgo. Así pues, el objetivo del presente estudio es evaluar el papel de factores psicológicos en la prevención de infecciones de transmisión sexual entre población joven. Para ello, 984 jóvenes de entre 18 y 24 años (32,7% hombres y 67,3…

030505 public healthinfección de transmisión sexualbusiness.industryprevenciónIncidence (epidemiology)Human sexualitypoblación jovenComputer-assisted web interviewinglaw.invention03 medical and health sciences0302 clinical medicineCondomlawMedicineAnxietyPornographyfactores de riesgo030212 general & internal medicineAge of onsetmedicine.symptom0305 other medical sciencebusinessReproductive healthDemography
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The experience of sexuality in adults with intellectual disability

2017

Background People with intellectual disability have the same sexual needs as those without any disability, yet their sexuality is often restricted by reluctant attitudes and/or fears based on irrational beliefs. The aim of this study is to describe and analyse different areas of sexuality in adults with mild or moderate intellectual disability. Method The sample consisted of 180 men and 180 women attending occupational centres. All the participants were administered a questionnaire about sexuality adapted to their characteristics. Results Results show that 84.2% have had sexual relationships with another person, this percentage being higher in females and in people aged between 38 and 55 ye…

030506 rehabilitationHuman sexualityIntrauterine devicelaw.invention03 medical and health sciencesArts and Humanities (miscellaneous)CondomlawIntellectual disabilitymedicine0501 psychology and cognitive sciencesReproductive healthbusiness.industry05 social sciencesRehabilitationmedicine.diseasePsychiatry and Mental healthNeurologySexual abusePillNeurology (clinical)Medical model of disability0305 other medical sciencebusinessPsychology050104 developmental & child psychologyClinical psychologyJournal of Intellectual Disability Research
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Actitudes hacia la sexualidad de las personas con discapacidad intelectual: ¿difiere la población general de las propias personas con discapacidad in…

2020

Un aspecto esencial para garantizar la calidad de vida en las personas con Discapacidad Intelectual (PDI) es la salud sexual. Pese a que en los últimos años se ha aumentado la atención en esta cuestión, es determinante conocer si existen prejuicios que pueden afectar al desarrollo saludable. El objetivo de este estudio ha sido comparar las actitudes hacia la sexualidad de las PDI que tienen ellas mismas con las que tiene la población general (PPG). Para ello un total de 100 PDI (50% hombres y 50% mujeres), de 19 a 55 años completaron la Escala de Percepción Sexual, y 454 PPG (39.4% hombres y 60.6% mujeres), de entre 20-82 años completaron la Escala de Actitudes para la Sexualidad en Persona…

030506 rehabilitationeducation.field_of_studybusiness.industry05 social sciencesPopulationHuman sexualityAttitude scalelaw.invention03 medical and health sciencesCondomlaw0501 psychology and cognitive sciencesPositive attitude0305 other medical scienceeducationbusinessPsychology050104 developmental & child psychologyClinical psychologyReproductive healthRevista INFAD de Psicología. International Journal of Developmental and Educational Psychology.
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Evaluation der Sexual Sensation Seeking Scale: Ergebnisse einer repräsentativen deutschen Bevölkerungsumfrage

2021

ZusammenfassungBisherige Studien zu Sexual Sensation Seeking (SSS) und der Sexual Sensation Seeking Scale (SSSS) wurden überwiegend an nach dem Alter sowie dem Geschlecht selektierten Stichproben durchgeführt. In dieser Arbeit wurde die deutsche Version der SSSS anhand einer repräsentativen Umfrage an Männern und Frauen evaluiert, welche die gesamte Altersspanne der erwachsenen deutschen Bevölkerung umfasst. Die Gütekriterien und die Faktorenstruktur der deutschen Version der Sexual Sensation Seeking Scale wurden anhand einer repräsentativen Stichprobe von N=2420 Probanden (54% Frauen, 46% Männer) im Alter von 18–93 Jahren (M=50,44, SD=16,97) untersucht. Die SSSS zeigt gute Werte hinsichtli…

050103 clinical psychologybusiness.industry05 social sciencesConstruct validity050109 social psychologyFactor structurelanguage.human_languageGermanPsychiatry and Mental healthClinical PsychologyConvergent validityGerman populationScale (social sciences)languageSensation seeking0501 psychology and cognitive sciencesPsychologybusinessApplied PsychologyClinical psychologyReproductive healthPPmP - Psychotherapie · Psychosomatik · Medizinische Psychologie
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2017

Importance: Comprehensive and timely monitoring of disease burden in all age groups, including children and adolescents, is essential for improving population health.Objective: To quantify and describe levels and trends of mortality and nonfatal health outcomes among children and adolescents from 1990 to 2015 to provide a framework for policy discussion.Evidence Review: Cause-specific mortality and nonfatal health outcomes were analyzed for 195 countries and territories by age group, sex, and year from 1990 to 2015 using standardized approaches for data processing and statistical modeling, with subsequent analysis of the findings to describe levels and trends across geography and time among…

2. Zero hungerGerontologyeducation.field_of_studybusiness.industryPopulation1. No poverty3. Good healthChild mortality03 medical and health sciencesEpidemiological transition0302 clinical medicine030225 pediatricsEnvironmental healthPediatrics Perinatology and Child HealthGlobal healthLife expectancyMedicine030212 general & internal medicinebusinesseducationDisease burdenReproductive healthAdolescent healthJAMA Pediatrics
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Capacity assessment for provision of quality sexual reproductive health and HIV-integrated services in Karamoja, Uganda

2020

Introduction: Sexual and reproductive health (SRH) and Human Immunodeficiency Virus (HIV) are crucial global health issues. Uganda continues to sustain a huge burden of HIV and AIDS.
 Methods: A cross-sectional health facility-based assessment was performed in November and December 2016 in Karamoja Region, northern Uganda. All the 126 health facilities (HFs) in Karamoja, including 5 hospitals and 121 Health Centers (HCs), covering 51 sub-counties of the 7 districts were assessed. We assessed the capacity of a) leadership and governance, b) human resource, c) service delivery, d) SRH and HIV service integration and e) users satisfaction and perceptions.
 Results: 64% of the establi…

AdultCapacity BuildingAdolescentService delivery framework030231 tropical medicineStaffingHIV InfectionsSettore MED/42 - Igiene Generale E ApplicataYoung Adult03 medical and health sciences0302 clinical medicineAcquired immunodeficiency syndrome (AIDS)Health facilitySurveys and QuestionnairesEnvironmental healthGlobal healthHumansMedicineUgandaHIV-Integrated ServicesHuman resourcesReproductive healthService (business)Delivery of Health Care Integratedbusiness.industryArticlesGeneral MedicineMiddle Agedmedicine.diseaseQuality Sexual Reproductive HealthQuality Sexual Reproductive Health HIV-Integrated Services Karamoja UgandaCross-Sectional StudiesReproductive HealthSocioeconomic FactorsFemaleReproductive Health ServicesHealth FacilitiesSexual HealthbusinessKaramoja
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Professional counseling in women with serious mental illness: achieving a shift toward a more effective contraceptive method.

2020

Mental disorders in reproductive-aged women have significant implications for the risk of unintended pregnancies. The objective of this study is to assess the professional counseling in clinical practice based on motivational interview in women with serious mental illness (SMI) in order to achieve a change to a more effective contraceptive method.A prospective observational cohort study (2012-2017) was conducted in a convenience sample of women with severe-moderate psychiatric disorders (After evidence-based counseling, 51.6% of participants changed their contraceptive method to a more effective one. This change was associated with gender violence (β coefficient = 1.58,Evidence-based contra…

AdultCounselingmedicine.medical_specialtygenetic structuresContraceptive counseling03 medical and health sciences0302 clinical medicinePregnancymedicineHumans030212 general & internal medicineProspective StudiesChildContraception BehaviorReproductive health030219 obstetrics & reproductive medicinebusiness.industryMental DisordersObstetrics and GynecologyMental illnessmedicine.diseasePsychiatry and Mental healthClinical PsychologyContraceptionReproductive MedicineFamily medicineFamily Planning ServicesFemalebusinessUnintended pregnancyJournal of psychosomatic obstetrics and gynaecology
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Reproductive health problems in rural South African young women: risk behaviour and risk factors

2018

Background South African young women continue to be vulnerable, with high prevalence of teenage pregnancy, HIV, sexually transmitted infections (STIs) and female genital schistosomiasis (FGS). This study seeks to examine the underlying factors that may be associated with these four adverse reproductive health outcomes. Methods In a cross-sectional study of 1413 sexually active of young women, we explored these four adverse reproductive health outcomes by considering socio-demographic factors, socio-economic factors, sexual risk behaviour, substance abuse and knowledge about reproductive health by using a questionnaire. Consenting participants were asked about previous pregnancies and were t…

AdultHealth Knowledge Attitudes Practicemedicine.medical_specialtyAdolescentSexual Behavior030231 tropical medicinePopulationSexually Transmitted DiseasesReproductive medicineHIV InfectionsHealth literacylcsh:Gynecology and obstetricsSouth Africa03 medical and health sciencesRisk-Taking0302 clinical medicine5. Gender equalityPregnancyRisk FactorsEnvironmental healthHealth carePrevalencemedicineHumans030212 general & internal medicineChildeducationlcsh:RG1-991Reproductive healthTeenage pregnancyeducation.field_of_studybusiness.industryResearchPublic healthInfant NewbornObstetrics and Gynecology3. Good healthCross-Sectional StudiesReproductive HealthReproductive MedicinePregnancy in AdolescenceFemaleRural areabusiness
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